The La Liga title race is heating up, and Barcelona will be looking to further their lead at the top of the table on Saturday, April 5, when they welcome Real Betis to the Estadi Olímpic Lluís Companys. The kick-off is scheduled for 3 PM ET. Barca grabbed another win last weekend, beating Girona convincingly. As for Betis, they also won on matchday 29, taking down Sevilla in a highly entertaining affair. Continue reading for the Barcelona vs Real Betis picks.
La Liga: Barcelona vs Real Betis Odds, Analysis, & Picks

Photo courtesy of Vincent Desjardins (Flickr), CC by 2.0
Highlights
- Barcelona and Real Betis meet on Saturday
- The hosts are a heavy favorite
- Read below for the odds, preview, and picks
Odds provided by Sports Interaction.
Barcelona vs Real Betis Odds
Moneyline | Barcelona -270 | Real Betis +600 |
Total Goals | Over 3.5 (-118) | Under 3.5 (-118) |
By no surprise, Barca is a heavy -270 favorite to win on Saturday. Betis comes back as a huge underdog at +600 at soccer betting sites. The Over/Under is set at 3.5 goals due to the high-scoring affairs in recent memory. The last five meetings all cashed the Over and Barcelona is unbeaten during that span, winning four of those matches.
Barcelona vs Real Betis Analysis
The La Liga title is very much in play for Barcelona, who are also in the quarterfinals of the Champions League. Hansi Flick’s men have a 21-3-5 record in Spain, sitting three points clear of rivals Real Madrid, who are in second place. The Catalans have bagged a mind-boggling 82 goals while conceding just 28. This attack has been on absolute fire all season long.
Robert Lewandowski is leading the way. The Poland international has scored 25 times already, while Brazilian Raphinha has 13 goals of his own as well. Ferran Torres, Lamine Yamal, and Dani Olmo are key contributors in the final third as well.
Lewandowski was the difference-maker in the 4-1 victory against Girona on matchday 29, netting a brace. Torres also scored while a Girona own goal was the cause for the fourth. Barca is riding an insane 21-game unbeaten run, last tasting defeat in December. They also beat Betis in the Copa del Rey Round of 16 a few months back.
Betis is having a respectable campaign of their own. They’re in sixth spot and just six points out of fourth place. The club has a 13-8-8 record and has won six games in a row. The victory over Sevilla in the Sevilla derby saw Cucho Hernandez bag the winner just before halftime.
Manuel Pelligrini’s side has also grabbed three victories in their last four matches away from home, which is a promising sign ahead of such a crucial encounter. The last time they beat Barcelona on the road was back in December of 2021.
Barcelona vs Real Betis Injury News
Barcelona is going to be without a plethora of players on Saturday, including Olmo, Marc Bernal, Andreas Christensen, Marc-Andre ter Stegen, and potentially Yamal, who is battling a minor knock. He cut his foot in the Copa del Rey on Wednesday. As for Betis, Marc Roca is doubtful due to injury, while former Real Madrid man Isco is serving a suspension. Man United loanee Antony will get another start amid his blistering form since arriving in Seville.
Barcelona vs Real Betis Picks
While I do believe Barcelona will secure another three points, the moneyline doesn’t offer much value. Instead, I’m eyeing the Over 3.5 goals due to the history between these two clubs. Expect lots of goals in Catalonia on Saturday.
Quinn Allen is a seasoned sports journalist from Vancouver, Canada. Quinn is a full-time senior editor for ClutchPoints where he specializes in baseball, soccer, basketball, and football. Quinn has been working in the industry for five years and brings a unique outlook to sports journalism, having played high-level soccer and baseball growing up. Quinn resides in Kelowna, Canada, and enjoys playing soccer and going to the gym.

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